Piper betle
Widely cultivated vine in South and Southeast Asia whose leaves are chewed as a stimulant, digestive aid, and breath freshener. Used in traditional medicine as an antiseptic, anti-inflammatory, and for respiratory disorders.
Oral submucous fibrosis (chronic chewing)
May interact with anticholinergic drugs. May affect blood sugar medications
Chronic chewing associated with oral cancer risk when combined with areca nut and lime. Staining of teeth
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