Griffonia

Griffonia simplicifolia

Family: Fabaceae Evidence: B capsuleextract

West African climbing plant whose seeds are the natural source of 5-HTP (5-hydroxytryptophan), a serotonin precursor used for mood and sleep support.

Safety Profile

PregnancyUnsafe
BreastfeedingUnsafe
PediatricNot Recommended

Contraindications

NOT with SSRIs, MAOIs, or serotonergic drugs (serotonin syndrome risk). Down syndrome.

Interactions

CRITICAL: Serotonin syndrome risk with antidepressants (SSRIs, SNRIs, MAOIs, triptans).

Side Effects

Nausea, GI upset, drowsiness. Serotonin syndrome if combined with serotonergic drugs.

Surgery: Discontinue 2 weeks before surgery.
This information is for educational purposes only. It is not medical advice. Consult a qualified healthcare provider before using any herbal product.