Kratom

Mitragyna speciosa

Family: Rubiaceae Evidence: D powdercapsuletea

A Southeast Asian tree with dose-dependent stimulant/sedative effects. HIGHLY CONTROVERSIAL — regulatory status varies. Significant safety concerns.

Safety Profile

PregnancyUnsafe
BreastfeedingUnsafe
PediatricNot Recommended

Contraindications

Pregnancy. Liver disease. Mental health conditions. Substance use disorders. Illegal or regulated in some jurisdictions.

Interactions

SIGNIFICANT interactions with opioids, sedatives, antidepressants, and all CNS-active drugs. Serotonin syndrome risk.

Side Effects

Nausea, constipation, dry mouth, drowsiness. Dependence and withdrawal possible with regular use. Rare: seizures, liver injury, death (usually with adulterants or combinations).

Surgery: Discontinue well before surgery. Inform anesthesiologist.
Liver: SERIOUS CONCERN: Multiple reports of liver injury. Cases of fatal hepatotoxicity.
This information is for educational purposes only. It is not medical advice. Consult a qualified healthcare provider before using any herbal product.