Silybum marianum
The most well-studied liver support herb. Silymarin, its active complex, has demonstrated hepatoprotective properties in numerous studies.
Asteraceae family allergy. Hormone-sensitive conditions (weak estrogenic activity).
May interact with medications metabolized by CYP2C9 and CYP3A4, diabetes medications, statins, and raloxifene.
Generally very well tolerated. Occasional GI upset, loose stools, allergic reactions.
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