SAMe

S-adenosylmethionine

Family: N/A (supplement) Evidence: A capsule

Not an herb but a naturally occurring molecule. Strong evidence for mood support, joint comfort, and liver health. Often included in herbal formularies.

Safety Profile

PregnancyInsufficient Data
BreastfeedingInsufficient Data
PediatricNot Recommended

Contraindications

Bipolar disorder (may trigger mania). NOT with SSRIs/MAOIs without supervision.

Interactions

CRITICAL: Serotonin syndrome risk with antidepressants. May interact with levodopa.

Side Effects

GI upset, anxiety, insomnia. May trigger mania in bipolar.

This information is for educational purposes only. It is not medical advice. Consult a qualified healthcare provider before using any herbal product.