St. John's Wort Extract

Hypericum perforatum (extract)

Standardized to 0.3% hypericin. Clinical evidence comparable to SSRIs for mild-moderate depression. CRITICAL drug interactions — the most interaction-prone herb.

Safety Profile

Contraindications

Bipolar. Photosensitivity. Surgery. MANY drug interactions.

Interactions

CRITICAL: Reduces effectiveness of OCP, HIV meds, transplant drugs, blood thinners, digoxin, chemo, SSRIs (serotonin syndrome).

Side Effects

Photosensitivity, GI upset, dizziness, dry mouth.