Berberine hydrochloride (500mg)
Isolated alkaloid from multiple plants (Goldenseal, Oregon Grape, Barberry, Coptis). 500mg 2-3x daily matches metformin for blood sugar in some studies. Also antimicrobial and cholesterol-lowering. The "natural metformin."
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If you take any medications, review these interactions carefully.
Diabetes meds (SIGNIFICANT), CYP enzymes (SIGNIFICANT), cyclosporine, metformin, macrolide antibiotics.
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GI upset, constipation, cramping, diarrhea. Headache.
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