Hypericum perforatum (0.3% hypericin)
German standardized extract — 300mg 3x daily (0.3% hypericin). Matches SSRIs for mild-moderate depression in meta-analyses. LI 160 and WS 5572 are the most-studied extracts. Full effect takes 4-6 weeks. THE most drug-interacting herb known.
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If you take any medications, review these interactions carefully.
SSRIs, oral contraceptives, HIV meds, warfarin, cyclosporine, digoxin, chemotherapy, statins, benzodiazepines — EXTENSIVE list.
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Discontinue 2+ weeks before surgery.
Photosensitivity, GI upset, fatigue, anxiety, dizziness, dry mouth.
Full dosage ranges, extraction ratios, and step-by-step preparation instructions for St Johns Wort Standardized are available to members.
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