Shiitake

Lentinula edodes

Evidence: AFamily: Marasmiaceae

Medicinal mushroom rich in lentinan beta-glucans; powerful immunomodulator with antitumor, antiviral, and hepatoprotective effects used adjunctively in veterinary oncology and immunity.

Consult Your Veterinarian First

This information is for educational purposes only. Always consult a qualified veterinarian before using herbal remedies for your pet — especially if they are on medication, pregnant, or have existing health conditions.

Species Safety

An herb safe for one species may be toxic to another.

Dogs

Safe

Duration: long term

Pregnancy: safeYoung: safe

Cats

Safe

Duration: long term

Pregnancy: safeYoung: safe

Horses

Safe

Duration: long term

Pregnancy: safeYoung: safe

Rabbits

Safe

Duration: moderate term

Pregnancy: safeYoung: safe

Birds

Safe

Duration: moderate term

Pregnancy: safeYoung: safe

Guinea Pigs

Safe

Duration: moderate term

Pregnancy: safeYoung: safe

Dosing Guide

General guidance only — always consult your veterinarian.

SpeciesFormDoseFrequencyNotes
Dogsdried herb0.25-0.5 grams /kgtwice dailyPer 10kg; hot water extract powder preferred for bioavailability of beta-glucans.
Catscapsule50-100 mg /kgtwice dailyPer 5kg; hot water extract preferred; immune support for FIV/FeLV/cancer.
Horsesdried herb10-30 gramsonce dailyFor 450kg horse; immune and oncology adjunct; extract forms top-dressed on feed.

Active Compounds

Lentinan(other)
Eritadenine(alkaloid)
Ergosterol(other)
KS-2 peptide(other)

Compounds marked Cat Unsafe (phenols and many terpenes) cannot be metabolized by feline livers.

Safety Warnings

Surgery Warning

Cook or use extracts; raw shiitake contains lentinan that can cause dermatitis in susceptible animals.

Essential Oil Form

Strong clinical evidence for lentinan in veterinary oncology; well-established immunomodulator.

Quick Info

Plant Family

Marasmiaceae

Parts Used

fruit, whole plant

Available Forms

dried herb, capsule, tea

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